Clostridium Difficile Toxin Gene Detection by DNA Amplification

This change will take effect May 17, 2012

Overview and Clinical Utility:
Because of their low sensitivity, enzyme immunoassay (EIA) tests are no longer recommended for detection of C. difficile toxin in stool specimens.1 Recent literature indicates that nucleic acid amplification-based assays provide sensitivities and specificities comparable to toxigenic culture, the current “gold standard” and provide significantly shorter turnaround times.

 

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